![]() Despite of these advantages, a proportion of patients receiving VATS still experience moderate to severe pain after surgery, and achievement of postoperative analgesia is still challenging. Thus, VAST has now been widely accepted and become the gold standard for many thoracic surgeries. Video-assisted thoracoscopic surgery (VATS), using a smaller incision, is less invasive and confers less postoperative pain than the traditional open thoracotomy. Thus, postoperative acute pain management is a very important issue for patients suffering postoperative pain. Insufficient postoperative pain control will delay the recovery of pulmonary function, increase the length of hospital stay, and lead to postoperative complications such as pulmonary infection, which is negatively related to quality of life and patient’s satisfaction. Patients undergoing thoracic surgery frequently experience acute and chronic postoperative pain. However, due to huge heterogeneity, more well-designed, large-scale RCTs are needed to verify these findings in the future. SAPB shows an excellent performance in postoperative pain management in patients undergoing VATS by reducing pains scores, postoperative opioid consumption and incidence of PONV. There was no difference between both groups regarding length of hospital stay and risk of dizziness. ResultsĪ total of 12 RCTs (837 participants) were finally included. Pooled relative risk (RR) with 95%CI were calculated for the risk of postoperative nausea and vomiting (PONV) and dizziness. Mean difference (MD) and corresponding 95% confidence interval (95%CI) were calculated for postoperative pain scores at various time points, postoperative opioid consumption and length of hospital stay. RCTs evaluating the analgesic performance of SAPB, comparing to control methods (no block, placebo or local infiltration anesthesia), in patients undergoing VATS were searched in PubMed, EMBASE, Web of Science and Cochrane Library from inception to December 31, 2022. Therefore, we conducted the present systematic review and meta-analysis. Till now, several randomized controlled trials (RCTs) have explored the effectiveness of SAPB for postoperative pain control in patients undergoing video-assisted thoracoscopic surgery (VATS), but the sample sizes were small and conclusions remained in controversy. Serratus anterior plane block (SAPB) is a promising regional technique for analgesia in thoracic surgery. ![]()
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